Tracing antigen signatures in the human IgE repertoire
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چکیده
منابع مشابه
Tracing antigen signatures in the human IgE repertoire
Allergen recognition by IgE antibodies is a key event in allergic inflammation. In this study, the IgE IGHV repertoires of individuals with allergy to the major birch pollen allergen, Bet v 1, were analyzed over a four years period of allergen exposure by RT-PCR and sequencing of cDNA. Approximately half of the IgE transcripts represented non-redundant sequences, which belonged to seventeen dif...
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ژورنال
عنوان ژورنال: Molecular Immunology
سال: 2010
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2010.05.285